


FBI agent Neville Flynn boards a flight from Honolulu, Hawaii to Los Angeles, escorting a key witness to testify against a mob boss at an upcoming trial. An on-board assassin releases a crate full of hundreds of deadly venomous snakes in an attempt to eliminate the witness. Flynn and a host of frightened passengers and crew must band together to survive the slithery threat.

Samuel L. Jackson
Neville Flynn

Julianna Margulies
Claire Miller

Nathan Phillips
Sean Jones

Kenan Thompson
Troy

Rachel Blanchard
Mercedes

Flex Alexander
Three G's

Keith Dallas
Big Leroy

Sunny Mabrey
Tiffany

Lin Shaye
Grace

Elsa Pataky
Maria
Bruce James
Ken

Casey Dubois
Curtis

Gerard Plunkett
Paul

Terry Chen
Chen Leong

Emily Holmes
Ashley

Mark Houghton
John Sanders

David Koechner
Rick

Bobby Cannavale
Hank Harris

Yan-Kay Crystal Lowe
Autograph Girl

Todd Louiso
Dr. Steven Price
David R. Ellis
John Heffernan, Sebastian Gutierrez
Released