John Candy

Jack Gable

Mariel Hemingway

Janet Dubois / Louise

Emma Samms

Rachel Hedison / Laura Claybourne

Raymond Burr

Carter Hedison

Dylan Baker

Blake Hedison

Charles Rocket

Ty Hedison

David Rasche

Dr. Paul Kirkwood / Dennis

Andrea Thompson

Nurse Helen Caldwell

Zach Grenier

Mickey

Jerry Orbach

Lou Sherwood

Renée Taylor

Arlene Sherwood

Milt Oberman

Fetterman

Mark Boone Junior

Cable Man

Tony Steedman

Edward

John Michael Bolger

Len

Rita Gomez

Marge

Stephanie Segal

TV Reporter

Mark Zuelke

Chauffeur

Dick Durock

Riley

Anthony G. Schmidt

Mason